11. Apr, 2016

Parkinsons Disease

Every hour, someone in the UK is told they have Parkinson's - a brain condition that turns lives upside down, leaving a future full of uncertainty. We know that Parkinson's can make people feel frightened, isolated and alone. We need to make sure that everyone affected by Parkinson's has the information and support they need. - See more at: http://www.parkinsons.org.uk/content/parkinsons-awareness-week-18-24-april-2016#sthash.V8uWWoEf.dpuf

 

Our list highlights Parkinson's research projects in the UK that are looking for participants.

Anyone with Parkinson's who is considering taking part in a research study should consult their neurologist.

Although some studies involve testing new Parkinson's treatments, many focus on helping us understand the condition better.

Our list is provided for information only. It should not be treated as advice or a recommendation to participate in any of the studies.

If you have Parkinson's and you're considering taking part in a research study, consult your neurologist and speak to the healthcare professionals managing the study.

Read more about taking part in clinical research in our 'Guide to clinical trials'

 

UK research studies that need participants are listed below.

  • Mood and help-seeking in Parkinson's

 This research study, led by a team at King's College London, is investigating people's knowledge and attitudes around mood problems such as depression or anxiety in Parkinson's. It also looks at what influences whether they seek help and who they ask.

  •  What: Participants will be invited to complete questionnaires in their own time and take part in an interview with the researcher.
  • Where: London, South East and South Wales
     
  • Who: People with Parkinson's (you do not need to have mood problems or have experienced them previously)
     
  • Deadline: 29 February 2016
     
  • Funded by: East Kent University Hospitals NHS Foundation Trust

 

Read more about the study in the information sheet:
Mood problems - patient information sheet (PDF, 157KB)

If you're interested in taking part, please contact
Anna Simpson, Institute of Psychiatry, London
020 7848 0890
anna.simpson@kcl.ac.uk

- See more at: http://www.parkinsons.org.uk/content/take-part-parkinsons-research-list-uk-studies#sthash.xz6pfoF5.dpuf

  • PDSAFE: can physiotherapy prevent falls?

PDSAFE is a personalised physiotherapy programme which aims to help with balance and movement. The purpose of this trial is to see if PDSAFE can help people with Parkinson's to fall less often and to assess whether it is cost-effective.

  • What: Participants will either receive PDSAFE personalised physiotherapy or remain on their usual care. All participants will have regular assessments and be asked to keep a diary of any falls they have. 
  • Where: Southampton, Portsmouth, Poole, Bournemouth, Exeter and surrounding areas
  • Who: 600 people with Parkinson's, living at home who have fallen at least once in the last year
  • Deadline: April 2016

Funded by: National Institute for Health Research Health Technology Assessment Programme

Read more about the study in the information sheet:
PDSAFE to prevent falls among people with Parkinson's - patient information sheet (PDF, 239KB)

If you're interested in taking part, please contact
Dr Kim Seymour, University of Southampton
023 8120 4943
Pdsafe@soton.ac.uk

  • Developing ways to measure pain in Parkinson's

 This study aims to develop and test the first ever pain scale specific to Parkinson's.

  •  What: Participants will be asked to complete a number of scales already in use as well as the PD pain scale with a doctor or nurse.
  • Where: London, Edinburgh, Sidcup, Bromley, Macclesfield, Salford and Plymouth
     
  • Who: People with Parkinson's who experience pain which is unrelated to other conditions
     
  • Deadline: December 2023
     
  • Funded by: Parkinson's UK

 Read more about the study in the information sheet:
PD pain scale - patient information sheet (PDF, 65KB)

 If you're interested in taking part, please contact
Ms Alex Rizos, King's College Hospital, London
0203 299 7153
a.rizos@nhs.net

- See more at: http://www.parkinsons.org.uk/content/take-part-parkinsons-research-list-uk-studies#sthash.xz6pfoF5.dpuf

  • Non-motor symptoms in early Parkinson's

This international study is investigating when symptoms such as sleep problems, fatigue, pain and depression occur during Parkinson's, how they develop and how they respond to treatments.

  • What: Participants will be asked to complete questionnaires about a wide range of symptoms and their quality of life at 6 month intervals.
  • Where: London, Kent, Norwich, Yeovil, Harrogate, Lincoln, Macclesfield and Grantham
  • Who: 1,000 people diagnosed with Parkinson's for 5 years or less
  • Deadline: February 2016

Funded by: Parkinson's Disease Non-Motor Group

Read more about the study in the information sheet:
Non-motor symptoms in early Parkinson's - study information sheet (PDF, 80KB)

If you're interested in taking part, please contact
Ms Alex Rizos, King's College Hospital, London
0203 299 7153
a.rizos@nhs.net

  • Investigating early onset Parkinson's

The researchers are studying people with early onset Parkinson's to understand more about the symptoms and genetics of the condition.
 

  • Where: UK wide
  • Who: 500 people diagnosed with Parkinson's before the age of 45
  • Deadline: Ongoing
  • Funded by: Parkinson's UK

If you're interested in taking part, please contact
Professor Huw Morris, National Hospital for Neurology, Queen Square
020 7794 0500 ext. 36833
h.morris@ucl.ac.uk

  • Investigating changes in thinking in Parkinson's

This project will investigate mental processing in Parkinson's. The researchers will study how people with Parkinson's choose the right thing to do at the right time compared to people without the condition.

  • What: Participants will be asked to do a range of tasks and undergo brain scans.
  • Where: Eastern England
  • Who: 40 people with Parkinson's and 40 people without any neurological condition
  • Deadline: December 2017
  • Funded by: The Wellcome Trust

 

Read more about the study here:
Understanding cognition and action in Parkinson's

If you're interested in taking part, please contact
Dr James Rowe, University of Cambridge
01223 273630
james.rowe@mrc-cbu.cam.ac.uk

  • Parkinson's Progressive Markers Initiative

The Parkinson's Progression Markers Initiative (PPMI) aims to identify risk factors for Parkinson's and ultimately lead to the development of tests that can be used to accurately diagnose and monitor the condition.

  • What: Participants will undergo a comprehensive series of assessments including brain scans; collection of blood, cerebral spinal fluid, and urine samples; as well as cognitive and motor evaluations. 
  • Where: London
  • Who: People who are of Eastern European (Ashkenazi) Jewish descent with Parkinson's (of any age) and without Parkinson's (over the age of 50 and related to someone who has Parkinson's. 
  • Deadline: Ongoing
  • Funded by: Michael J Fox Foundation

Read more about the study here:
Parkinson's Progression Markers Initiative

If you're interested in taking part, please contact
Bina Shah, Charing Cross Hospital
020 3311 1714
Parkinson.ResearchTeam@imperial.nhs.uk

  • Representing action in Parkinson's
  • The research team are interested in how people with Parkinson's respond to different objects and movements in their environment and how well they can communicate.
  • What: Participants will be asked to watch some video clips and look at pictures while the team measures your reaction times, eye and hand movements.
  • Where: Greater Manchester
  • Who: 25 people with Parkinson's and 25 people without Parkinson's, all aged 50-75
  • Deadline: April 2016
  • Funded by: The University of Manchester

Read more about the study in the information sheet:
Representing action - study leaflet (people with Parkinson's) (PDF, 185KB)
Representing action - study leaflet (people without Parkinson's) (PDF, 143KB)
Representing action - participant information leaflet (PDF, 151KB)

If you're interested in taking part, please contact
Ellen Poliakoff, University of Manchester
0161 275 7333
Ellen.Poliakoff@manchester.ac.uk

  • Examining eye movements in people with Parkinson's

In this study, the research team will explore whether eye movement responses to different stimuli are affected in people with Parkinson's.

  • What: Participants will be asked to undergo tests of their eye movement responses to different stimuli.
  • Where: Oxford
  • Who: 400 people diagnosed with Parkinson's for 5 years or less and 200 people who do not have Parkinson's (or any other neurodegenerative condition)
  • Deadline: December 2016
  • Funded by: The Wellcome Trust

If you're interested in taking part, please contact
Dr Chrystalina Antoniades, John Radcliffe Hospital, Oxford University
01865 234728
chrystalina.antoniades@clneuro.ox.ac.uk

  • Vision and sense of smell in Parkinson's

This study aims to explore the relationship between vision and sense of smell in people with Parkinson's.

  • What: Participants will take part in sight and smell tests and share details of their Parkinson's through questionnaires.
  • Where: Bournemouth, Poole, Christchurch and surrounding areas
  • Who: People with Parkinson's 
  • Deadline: Ongoing
  • Funded by: NA

Read more about the study in the information sheet:
Visual perception and sense of smell - patient information sheet (Word, 228KB)

If you're interested in taking part, please contact
Professor Ahmed Khattab, Bournemouth University
01202 967281
akhattab@bournemouth.ac.uk

  • Developing the best care possible for Parkinson’s

This study aims to see if specialist care can improve the control of symptoms and provide support for people with Parkinson’s and those close to them.

  • What: Questionnaires and short-term palliative care lasting up to 24 weeks  
  • Where: Brighton, Cardiff, South London, Liverpool and Nottingham. Participants must live within the catchment areas of trial sites. You can find more information on catchment areas here: http://bit.ly/1RoQu4m
  • Who: People with Parkinson’s who are not currently receiving palliative care
  • Deadline: 31st December 2016
  • Funded by: NIHR Health Services & Delivery Research Programme

Read more about the study in the information sheet:

OPTCARE Participant Information Sheet (PDF,379KB)

 

If you're interested in taking part, please contact
Debbie Tonkin, King's College London
0207 848 5578
deborah.tonkin@kcl.ac.uk

  • Learning new movements with Parkinson’s

This study aims to understand how people with Parkinson’s learn new movements. The researchers will investigate the ability for people with Parkinson’s to remember new movements.

  •  What:  The study will involve up to 3 sessions, lasting no more than 90 minutes each. Participants will be asked to perform simple tasks that involve hand, arm and eye movements during these sessions.
  • Where: Birmingham or the West Midlands.
  • Who: People with and without Parkinson’s
  • Deadline: 31st September 2018
  • Funded by: Parkinson’s UK

Read more about the study in the information sheet:

Motor Control- Participant Information Sheet (PDF,234KB)

 

If you’re interested in taking part, please contact:

Sarah Voets, University of Birmingham
07823615520
SHV575@bham.ac.uk

  • Hallucinations in people with Parkinson’s

This study aims to improve our understanding of visual hallucinations in people with Parkinson’s.

  •  What: Participants will be invited to take part in face-to-face and follow-up over the phone assessments
  • Where: London, Cambridge or Newcastle
  • Who: People with Parkinson’s with and without experience of hallucinations 
  • Deadline: 31st December 2016
  • Funded by: National Institute for Health Research (NIHR)

Read more about the study in the information sheet:

Shaped- Participant Information Sheet (PDF,332KB)

 

If you’re interested in taking part, please contact:

London- Dr Rebecca Pinto, Kings College London 
0207 848 0297 
Rebecca.pinto@kcl.ac.uk

Cambridge- Kate Harris, University of Cambridge 
01223 331141 
kh600@cam.ac.uk

Newcastle- Kirsty Olsen, University of Newcastle 
0191 208 1344 
Kirsty.olsen@ncl.ac.uk

  • Mindfulness therapy for people with Parkinson’s

This study aims to understand if a mindfulness-based course can reduce depression and anxiety.

  •  What: Participants will be asked to take part in 8 once weekly sessions of a mindfulness course. The course will be delivered via Skype video conferences.
  • Where: UK-wide
  • Who: People with Parkinson’s who have computer and internet access at home
  • Deadline: June 2016
  • Funded by: Parkinson’s UK

Read more about the study in the information sheet:

Mindfulness- Information Sheet (PDF,109KB)

 

If you’re interested in taking part, please contact:
Dr Debora Sa, City University London
07399 094791 
Debora.v.sa@city.ac.uk

  • 100 for Parkinson's

This research study aims to find out if daily health tracking via a smartphone and/or tablet can improve the quality of people’s lives.

  •  What: Participants will be asked to use a new mobile application (app) for a period of 100 days
  • Where: UK-wide
  • Who: People with and without Parkinson's who have access to a smartphone and/or tablet on a daily basis
  • Deadline: November 2016 
  • Funded by: UMotif Ltd and its partners

 

Read more about the study in the information sheet:

100forParkinson's Information Sheet (PDF,455KB)

If you’re interested in taking part, please visit the UMotif website www.100forparkinsons.com 

  • Recognising emotions with Parkinson's

This research study, led by a team at Newcastle University, is investigating how easy it is for people with Parkinson’s to recognise different emotions.

  •  What: Participants will be asked to make several visits to the university lasting between 2-4 hours. Sessions will involve looking at a series of photographs on a computer screen.
  • Where: Newcastle upon Tyne and surrounding areas
  • Who: People with and without Parkinson's who are over 50 and are not blind or sight impaired
  • Deadline: 1st December 2016 
  • Funded by: National Institute of Health Research (NIHR)

Read more about the study in the information sheet:

SPiEs Participant Information Sheet (PDF,1.74MB)

If you’re interested in taking part, please contact:
Dr Joanna Wincenciak, Newcastle University
0191 208 1289 
Joanna.wincenciak@ncl.ac.uk

  • A therapy for Parkinson's-associated dementias

- Please visit this link for more information on these studies: http://www.parkinsons.org.uk/content/take-part-parkinsons-research-list-uk-studies#sthash.xz6pfoF5.dpuf